Revolutionizing Cell Therapy through Novel 3D Reprogramming

Building on iCamuno’s groundbreaking research in somatic cell reprogramming and the epigenetic dynamics of cell fate regulation in human embryonic development, we have ushered in a new generation of somatic cell induction reprogramming techniques. This has led to the creation of enhanced pluripotent stem cells, known as iCam-iPSCs. The epigenomic profile of these iCam-iPSCs aligns more closely with that of human embryonic stem cells (ESCs).
  • Healthy Donor Cells
    Healthy Donor Cells
  • Induced Pluripotent Stem Cells (iPSCs)
    Induced Pluripotent Stem Cells (iPSCs)
  • Engineered Modifications
    Engineered Modifications
  • Culture and Expansion
    Culture and Expansion

Technology Platforms

  • Blood cells

    Blood cells

  • Skin cells

    Skin cells

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Tumor immunity
Regenerative
Drug screening

iCam-iPSC: An Enhanced Pluripotent Stem Cell Platform

iCamuno’s expert team leverages key research findings, as outlined in three published articles in Nature and one in Nature Methods, to form the theoretical foundation that fuels technological innovation with an in-depth understanding of cell fate regulation. By addressing epigenetic abnormalities in iPSC reprogramming, we have derived enhanced pluripotent stem cells, known as iCam-iPSCs. These cells are closer in nature to embryonic stem cells (ESCs), offering heightened safety and pluripotency.

iCam-Intelligent Engineering Platform

iCamuno’s gene editing platform employs innovative technology to enhance the precision, reliability, and efficiency of gene editing processes. We harness these advancements to optimize the targeting, endurance, and safety of immunotherapy cells, amplifying their effectiveness in combating tumors.

iCam-AI-driven Expansion and Differentiation Platform

By integrating bioinformatic algorithms with single-cell multi-omics, we formulate innovative protocols that significantly enhance the efficiency and functionality of iPSC expansion and differentiation. This optimization results in more effective effector cells for applications in tumor immunotherapy—including natural killer cells, T-cells, and macrophages—and regenerative medicine—spanning mesenchymal stem cells, cardiomyocytes, dopaminergic neurons, and pancreatic islets.

Acknowledged Achievements

Through the deployment of sophisticated somatic cell reprogramming technology, iCamuno Biotherapeutics has made a historic breakthrough by constructing the world’s inaugural human blastocyst-like structure, the iBlastoid. This monumental accomplishment served as the foundation for a feature article on the cover of Nature.
Vice Chairman Unit of Jiangsu Biotechnology Association
Vice Chairman Unit of Jiangsu Biotechnology Association
Jiangsu Province
2021 China’s Top 50 Most Innovative Biopharmaceutical Enterprises
2021 China’s Top 50 Most Innovative Biopharmaceutical Enterprises
Third-Party (Star Researcher)
Science and Technology-based Small and Medium-sized Enterprise Award
Science and Technology-based Small and Medium-sized Enterprise Award
China
Innovative Small and Medium-sized Enterprise Award
Innovative Small and Medium-sized Enterprise Award
China